Xiangling Meng

Oct 16, 2024 | cell.com | Ji-il Kim |Yuki Miura |Min-Yin Li |Omer Revah |Sridhar Selvaraj |Fikri Birey | +6 more

KeywordsassembloidsorganoidsthalamusthalamocorticaldiseaseGet full text accessLog in, subscribe or purchase for full access. References1. Sherman, S.M. ∙ Guillery, R.W.The role of the thalamus in the flow of information to the cortexPhilos. Trans. R. Soc. Lond. B Biol. Sci. 2002; 357:1695-17082. Rikhye, R.V. ∙ Gilra, A. ∙ Halassa, M.M.Thalamic regulation of switching between cortical representations enables cognitive flexibilityNat. Neurosci. 2018; 21:1753-17633. Roy, D.S. ∙ Zhang, Y. ∙ Aida, T. ...

Apr 24, 2024 | nature.com | Xiaoyu Chen |Fikri Birey |Min-Yin Li |Noah Reis |Jin Hao |Xiangling Meng

AbstractTimothy syndrome (TS) is a severe, multisystem disorder characterized by autism, epilepsy, long-QT syndrome and other neuropsychiatric conditions1. TS type 1 (TS1) is caused by a gain-of-function variant in the alternatively spliced and developmentally enriched CACNA1C exon 8A, as opposed to its counterpart exon 8.

Sep 27, 2023 | nature.com | Xiangling Meng |Kent Imaizumi |Noah Reis |Michael Bassik

AbstractThe assembly of cortical circuits involves the generation and migration of interneurons from the ventral to the dorsal forebrain1,2,3, which has been challenging to study at inaccessible stages of late gestation and early postnatal human development4.