Norbert Solymosi

May 17, 2024 | biorxiv.org | Norbert Solymosi |Adrienn Gréta Tóth |Sara Nagy |István Csabai

AbstractAntimicrobial resistance (AMR) is one of our greatest public health challenges. Targeted use of antibiotics (AB) can reduce the occurrence and spread of AMR and boost the effectiveness of treatment. This requires knowledge of the antibiotic susceptibility (AS) of the pathogens involved in the disease. Therapeutic recommendations based on classical antibiotic susceptibility testing (AST) are based on the analysis of only a fraction of the bacteria present in the disease process.

Oct 19, 2023 | nature.com | Sándor Spisák |Bálint Ármin Pataki |Dezso Ribli |Connor Bell |Mersedeh Rohanizadegan |Sarah Abou Alaiwi | +8 more

Correction to: Nature Communications https://doi.org/10.1038/s41467-023-40616-z, published online 23 Aug 2023In this article, the author’s name Alan H. Bartels was incorrectly written as Alan B. Bartels. The original article has been corrected.

Aug 23, 2023 | nature.com | Sándor Spisák |Bálint Ármin Pataki |Connor Bell |Sarah Abou Alaiwi |Márton Papp |Xianzhi Lin | +8 more

AbstractTo date, single-nucleotide polymorphisms (SNPs) have been the most intensively investigated class of polymorphisms in genome wide associations studies (GWAS), however, other classes such as insertion-deletion or multiple nucleotide length polymorphism (MNLPs) may also confer disease risk. Multiple reports have shown that the 5p15.33 prostate cancer risk region is a particularly strong expression quantitative trait locus (eQTL) for Iroquois Homeobox 4 (IRX4) transcripts.

Aug 4, 2023 | biorxiv.org | István Csabai |Norbert Solymosi |Eötvös Loránd |Regina Nora Fiam

Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.

May 20, 2023 | nature.com | Norbert Solymosi

AbstractTick-borne infections, including those of bacterial origin, are significant public health issues. Antimicrobial resistance (AMR), which is one of the most pressing health challenges of our time, is driven by specific genetic determinants, primarily by the antimicrobial resistance genes (ARGs) of bacteria. In our work, we investigated the occurrence of ARGs in the genomes of tick-borne bacterial species that can cause human infections.