Ny Usa

Jan 8, 2025 | ejso.com | Ny Usa

Key wordspatient metabolic profilingPETMetPET-CTgastric cancerpathologic responseGet full text accessLog in, subscribe or purchase for full access. References1. Bang, Y.J. ∙ Van Cutsem, E. ∙ Feyereislova, A. ... Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trialLancet. 2010; 376:687-6972. Smyth, E.C. ∙ Wotherspoon, A. ∙ Peckitt, C. ...

Oct 25, 2024 | biorxiv.org | Ali Sonay |Jan Grimm |Ny Usa |Elana Apfelbaum

AbstractFerroptosis emerged as a cell death modality for drug resistant cancer cells, but there are currently no available biomarkers for imaging ferroptosis based therapies. To address this gab, we evaluated the nanodynamic changes in lipid membranes occurring during cell death to explore potential targeting opportunities to image cell death. We nano-sized gaps at late stages of ferroptosis can serve as entry points for dyes that can bind to cellular structures.

Jun 12, 2024 | academic.oup.com | Ny Usa

Subcluster analysis is a powerful means to improve clustering and characterization of single cell RNA-Seq data. However, there are no existing tools to systematically integrate results from multiple subclusters, which creates hurdles for accurate data quantification, visualization, and interpretation in downstream analysis. To address this issue, we developed Ragas, an R package that integrates multi-level subclustering objects for streamlined analysis and visualization.

Mar 21, 2024 | academic.oup.com | Ny Usa

Due to the link between microglial morphology and function, morphological changes in microglia are frequently used to identify pathological immune responses in the central nervous system. In the absence of pathology, microglia are responsible for maintaining homeostasis, and their morphology can be indicative of how the healthy brain behaves in the presence of external stimuli and genetic differences.

Dec 15, 2023 | uk.advfn.com | Ny Usa

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