Parvez Mantry

Jun 25, 2024 | onlinelibrary.wiley.com | Tarek Hassanein |Andrew Keaveny |Parvez Mantry |Alastair Smith

We appreciate the editorial comments by Minciuna and Stefanescu1 regarding the key findings of our study.2 As highlighted by them, unlike elastography and other biomarkers which are surrogates for staging fibrosis, the HepQuant SHUNT and DuO tests uniquely quantify functional hepatic mass, hepatic perfusion and portal-systemic shunting. The test is based on the liver-specific uptake of cholate.

May 22, 2024 | onlinelibrary.wiley.com | Tarek Hassanein |Andrew Keaveny |Parvez Mantry |Alastair Smith

Background The quantitative HepQuant SHUNT test of liver function and physiology generates a disease severity index (DSI) that correlates with risk for clinical complications, such as large oesophageal varices (LEVs). A derivative test, HepQuant DuO, generates an equivalent DSI and simplifies testing by requiring only oral administration of the test solution and two blood samples at 20 and 60 min.