Patrick Bordes

Dec 4, 2023 | biorxiv.org | Louis Robinson |Timothy Atkinson |Liviu Copoiu |Patrick Bordes

AbstractUnderstanding protein function is vital for drug discovery, disease diagnosis, and protein engineering. While Protein Language Models (PLMs) pre-trained on vast protein sequence datasets have achieved remarkable success, equivalent Protein Structure Models (PSMs) remain underrepresented. We attribute this to the relative lack of high-confidence structural data and suitable pre-training objectives.