Louis Robinson

Mar 22, 2024 | biorxiv.org | Thomas Barrett |Amelia Villegas-Morcillo |Louis Robinson |Benoit Gaujac

AbstractIn recent years, machine learning approaches for de novo protein structure prediction have made significant progress, culminating in AlphaFold which approaches experimental accuracies in certain settings and heralds the possibility of rapid in silico protein modelling and design.

Dec 4, 2023 | biorxiv.org | Louis Robinson |Timothy Atkinson |Liviu Copoiu |Patrick Bordes

AbstractUnderstanding protein function is vital for drug discovery, disease diagnosis, and protein engineering. While Protein Language Models (PLMs) pre-trained on vast protein sequence datasets have achieved remarkable success, equivalent Protein Structure Models (PSMs) remain underrepresented. We attribute this to the relative lack of high-confidence structural data and suitable pre-training objectives.