Patrick Morris

Jul 15, 2024 | pharmrev.aspetjournals.org | Panos Zanos |Ruin Moaddel |Patrick Morris |Lace M. Riggs

AbstractKetamine, a racemic mixture consisting of (S)- and (R)-ketamine, has been in clinical use since 1970. Although best characterized for its dissociative anesthetic properties, ketamine also exerts analgesic, anti-inflammatory, and antidepressant actions. We provide a comprehensive review of these therapeutic uses, emphasizing drug dose, route of administration, and the time course of these effects.