Paul R. B

Oct 26, 2024 | scholarsarchive.byu.edu | Brigham Young |Paul R. B

Keywordslipid A, LA, antibiotics, lipopolysaccharide, LPSCollegePhysical and Mathematical SciencesDepartmentChemistry and BiochemistryAbstractSeptic shock is a disease that kills over 100,000 hospitalized patients in the United States every year.

Oct 26, 2024 | scholarsarchive.byu.edu | William Thomas |Brigham Young |Paul R. B

Keywordsdevelopment, sugar receptor, oligosaccharidesCollegePhysical and Mathematical SciencesDepartmentChemistry and BiochemistryAbstractOligosaccharides are enormously rich in structural information.

Oct 26, 2024 | scholarsarchive.byu.edu | David Michaelis |Brigham Young |Paul R. B

Keywordsmetal ion chemosensor, cadmium, natural resourcesCollegePhysical and Mathematical SciencesDepartmentChemistry and BiochemistryAbstractAs society today continues to evolve technologically at a rapid rate, problems dealing with contamination of our natural resources become increasingly complex. Not only are new toxins introduced into the environment, but selective detection and removal of these contaminants proves ever more difficult.

Oct 26, 2024 | scholarsarchive.byu.edu | Jeffrey Clark |Brigham Young |Paul R. B

Keywordsthin film solutions, widespread hospital infection, ceageninCollegePhysical and Mathematical SciencesDepartmentChemistry and BiochemistryAbstractOne current problem in medicine is the accumulation of biofilm on medical devices. Bacterial colonization of endotracheal tubes and urinary catheters is the leading cause of hospital-acquired infections. These infections contribute significantly to patient mortality rates and care costs1.

Jul 9, 2024 | scholarsarchive.byu.edu | Katie Jensen |Brigham Young |Paul R. B

Keywordscholic acid-derived antibiotics, electron microscopic analysis, steroid antibioticsCollegePhysical and Mathematical SciencesDepartmentChemistry and BiochemistryAbstractPathogenic bacterial resistance to antibiotics has risen sharply over the past two decades.1 This problem is compounded with Gram-negative bacteria, which, in addition to developing specific resistant mechanisms, also display membrane structures that are impermeable to many hydrophobic antibiotics.