Paulina Rybakowska

Jun 1, 2024 | biorxiv.org | Paulina Rybakowska |Sofie Van Gassen |Guillermo Barturen |Carlos Pérez Sánchez |Carlos Sanchez

AbstractBackground: Systemic autoimmune diseases (SADs) are characterized by internal heterogeneity, overlapping clinical symptoms, and shared molecular pathways. Therefore, they are difficult to diagnose and new tools allowing precise diagnosis are needed. Molecular-based reclassification studies enable to find patterns in a diagnosis-independent way. Objective: To evaluate the possibility of using high-content immunophenotyping for detecting patient subgroups in the context of precise treatment.