Payal Chandak

Dec 4, 2024 | onlinelibrary.wiley.com | Yang Gao |Xiang Zhang |Zhongquan Sun |Payal Chandak

1 Introduction Adverse Drug Reactions (ADRs)[1-5] encompass undesired or detrimental effects resulting from the administration of medical products. The U.S. Food and Drug Administration (FDA) provides alarming statistics,[6] estimating that annually, over 2 216 000 severe ADRs occur in hospitalized patients, leading to more than 106 000 deaths.

Dec 4, 2024 | advanced.onlinelibrary.wiley.com | Yang Gao |Xiang Zhang |Zhongquan Sun |Payal Chandak

1 Introduction Adverse Drug Reactions (ADRs)[1-5] encompass undesired or detrimental effects resulting from the administration of medical products. The U.S. Food and Drug Administration (FDA) provides alarming statistics,[6] estimating that annually, over 2 216 000 severe ADRs occur in hospitalized patients, leading to more than 106 000 deaths.

Feb 2, 2023 | nature.com | Payal Chandak |Marinka Zitnik

AbstractDeveloping personalized diagnostic strategies and targeted treatments requires a deep understanding of disease biology and the ability to dissect the relationship between molecular and genetic factors and their phenotypic consequences. However, such knowledge is fragmented across publications, non-standardized repositories, and evolving ontologies describing various scales of biological organization between genotypes and clinical phenotypes.