Pengyi Yang

Jun 3, 2024 | biorxiv.org | Agus Salim |Dharmesh D. Bhuva |Pengyi Yang

AbstractLibrary size normalisation is necessary to enable comparisons between observations in transcriptomic datasets. Numerous methods have been developed to normalise these effects with sample and gene specific adjustments. However, in spatial transcriptomics data, normalisation is complicated by the fact that spatial region-specific library size confounds biology.

Dec 5, 2023 | biorxiv.org | Jieun Kim |Pengyi Yang

AbstractThe identification of genes that vary across spatial domains in tissues and cells is an essential step for spatial transcriptomics data analysis. Given the critical role it serves for downstream data interpretations, various methods for detecting spatially variable genes (SVGs) have been proposed.

Jun 20, 2023 | biorxiv.org | Elijah Willie |Pengyi Yang |Ellis Patrick

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