Peter DeWeirdt

Jan 7, 2025 | biorxiv.org | Peter DeWeirdt |Emily Mahoney |Michael T. Laub

AbstractAnti-phage defense systems protect bacteria from viruses. Studying defense systems has begun to reveal the evolutionary roots of eukaryotic innate immunity and produced important biotechnologies such as CRISPR-Cas9. Dozens of new systems have been discovered by looking for systems that co-localize in genomes, but this approach cannot identify systems outside defense islands.