Philip Quirke

Aug 7, 2024 | nature.com | Alex J. Cornish |Andreas Gruber |Ben Kinnersley |Anna Frangou |Giulio Caravagna |Boris Noyvert | +23 more

AbstractColorectal carcinoma (CRC) is a common cause of mortality1, but a comprehensive description of its genomic landscape is lacking2,3,4,5,6,7,8,9. Here we perform whole-genome sequencing of 2,023 CRC samples from participants in the UK 100,000 Genomes Project, thereby providing a highly detailed somatic mutational landscape of this cancer.

Apr 8, 2024 | nature.com | Enric Domingo |Leslie Samuel |Susan D. Richman |Andrew Blake |Philip Dunne |Philip Quirke | +2 more

AbstractThe development of deep learning (DL) models to predict the consensus molecular subtypes (CMS) from histopathology images (imCMS) is a promising and cost-effective strategy to support patient stratification.