Philipp M. Lepper

Mar 18, 2024 | respiratory-research.biomedcentral.com | Frank Langer |Philipp M. Lepper |Robert Bals |Heinrike Wilkens |Bettina Weingard |Parviz Aliyev

Underlying disease was classified as restrictive (n = 18 / 56%) or obstructive (n = 12 / 38%) lung disease (Table 1: Demographic data and postoperative outcome). Two patients with prior sLTx bronchiolitis obliterans syndrome (BOS 6%) underwent sLTx of the native contralateral lung. Sex was distributed equally (male n = 16, female n = 16) among recipients—recipient age ranged from 38 to 67 years (mean 58 ± 7 years). A high LAS (> 50) was present in 6 patients, median LAS was 38 (range 31–92).

Mar 18, 2024 | respiratory-research.biomedcentral.com | Frank Langer |Philipp M. Lepper |Robert Bals |Heinrike Wilkens |Bettina Weingard |Parviz Aliyev

Underlying disease was classified as restrictive (n = 18 / 56%) or obstructive (n = 12 / 38%) lung disease (Table 1: Demographic data and postoperative outcome). Two patients with prior sLTx bronchiolitis obliterans syndrome (BOS 6%) underwent sLTx of the native contralateral lung. Sex was distributed equally (male n = 16, female n = 16) among recipients—recipient age ranged from 38 to 67 years (mean 58 ± 7 years). A high LAS (> 50) was present in 6 patients, median LAS was 38 (range 31–92).

Jun 5, 2023 | jamanetwork.com | Philipp M. Lepper |Sebastian Mang |Torben M. Rixecker |Pascal Espig

Daratumumab for a Patient With Refractory Antineutrophil Cytoplasmatic Antibody–Associated Vasculitis Antineutrophil cytoplasmatic antibody (ANCA)–associated vasculitis (AAV) is characterized by multisystem organ involvement with necrotizing granulomatous inflammation and vasculitis.1 ANCA antibodies are considered both specific and pathogenic for this group of autoimmune diseases.2 Hence, B-cell depletion by anti-CD20 therapy has shown substantial benefit and is now considered the standard...