Pooja Swali

Jan 10, 2024 | nature.com | Kyriaki Anastasiadou |Marina Silva |Thomas C Booth |Christopher Barrington |Pooja Swali |Ian Armit | +4 more

AbstractAncient DNA is a valuable tool for investigating genetic and evolutionary history that can also provide detailed profiles of the lives of ancient individuals. In this study, we develop a generalised computational approach to detect aneuploidies (atypical autosomal and sex chromosome karyotypes) in the ancient genetic record and distinguish such karyotypes from contamination. We confirm that aneuploidies can be detected even in low-coverage genomes ( ~ 0.0001-fold), common in ancient DNA.

May 31, 2023 | inkl.com | Pooja Swali

Working with the University of Oxford, the Levens Local History Group and the Wells and Mendip Museum, the team took small skeletal samples from 34 individuals across the two sites, looking for the presence of Yersinia pestis in teeth. This technique involves drilling into the tooth and extracting dental pulp, which can trap DNA remnants of infectious diseases.

May 30, 2023 | inkl.com | Pooja Swali

Working with the University of Oxford, the Levens Local History Group and the Wells and Mendip Museum, the team took small skeletal samples from 34 individuals across the two sites, looking for the presence of Yersinia pestis in teeth. This technique involves drilling into the tooth and extracting dental pulp, which can trap DNA remnants of infectious diseases.