Prakhar Agrawal

Nov 21, 2024 | youthincmag.com | Prakhar Agrawal

Workplace health and safety have become key components of corporate operations in recent years. Ensuring employees’ well-being has a direct influence on productivity and the entire work environment. Businesses that prioritize proactive health and safety measures can minimize risks and expenses over time. Failure to address safety concerns can have serious implications, including legal challenges, penalties, and a tarnished reputation.

Nov 10, 2024 | tandfonline.com | Mandeep Kaur |Gurpal Singh |Ganesan Senthil Kumar |Prakhar Agrawal

AbstractThe cleavage and polyadenylation step are indispensable for pre-mRNA processing in eukaryotes. Defective 3′- end maturation of precursor mRNA has catastrophic effects, leading to several diseases in humans. This processing is orchestrated by a complex machinery comprising more than 20 proteins in Saccharomyces cerevisiae. Endonucleolytic cleavage followed by the addition of poly(A) tail at the 3′-end of the precursor mRNA requires CPF, CF IA and CF IB proteins.