Pranam Chatterjee

Aug 1, 2024 | biorxiv.org | Tong Chen |Yinuo Zhang |Pranam Chatterjee

AbstractThe ability to precisely target specific motifs on disease-related proteins, whether conserved epitopes on viral proteins, intrinsically disordered regions within transcription factors, or breakpoint junctions in fusion oncoproteins, is essential for modulating their function while minimizing off-target effects. Current methods struggle to achieve this specificity without reliable structural information.

Jul 31, 2024 | nature.com | Pranam Chatterjee

In a new study published in Cell Research, Chinese researchers have trained ProMEP, a multimodal protein representation model that enables accurate, zero-shot prediction of mutation effects in proteins.

Dec 5, 2023 | newsbreak.com | Pranam Chatterjee

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