-
3 weeks ago | 
onlinelibrary.wiley.com | Ruichen Jiang |Xudong WANG |Tong Chen |Shaoyu Guan
AAV adeno-associated virus BBB blood–brain barrier BMECs brain microvascular endothelial cells CNS central nervous system ELISA Enzyme linked immunosorbent assay GFP green fluorescent protein KEGG Kyoto Encyclopedia of Genes and Genomes LPS lipopolysaccharides LSD least significant difference LSZ ligustrazine MCAO middle cerebral artery occlusion miRNA microRNA NC negative control OGD oxygen–glucose deprivation qRT-PCR quantitative real-time PCR RIN RNA integrity number TJs tight junction...
-
Jan 9, 2025 | 
dx.doi.org | Chao Shen |Xiaoqi Han |Tong Chen
-
Dec 7, 2024 | 
arxiv.org | Nguyen Viet |Tong Chen |Wentao Zhang |Yuan Yuan
-
Oct 17, 2024 | 
mdpi.com | Yanping Wang |Xiaomei Wang |Rui Wen Zhang |Tong Chen
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
-
Aug 1, 2024 | 
biorxiv.org | Tong Chen |Yinuo Zhang |Pranam Chatterjee
AbstractThe ability to precisely target specific motifs on disease-related proteins, whether conserved epitopes on viral proteins, intrinsically disordered regions within transcription factors, or breakpoint junctions in fusion oncoproteins, is essential for modulating their function while minimizing off-target effects. Current methods struggle to achieve this specificity without reliable structural information.
-
Jul 17, 2024 | 
chaseedesign.com.au | Tong Chen
Discover how to create inclusive websites that serve all users. Learn key accessibility practices, emerging trends, and the impact on user experience and SEO.
-
Jun 26, 2024 | 
acamh.onlinelibrary.wiley.com | Tong Chen |Olakunle Oginni |Laurie J. Hannigan |Thalia C. Eley
While it has been theorized that emotional problems during childhood and adolescence can be associated with alcohol use behaviors in adolescence and adulthood (e.g. Zucker, 2006; Zucker, Donovan, Masten, Mattson, & Moss, 2008), empirical evidence has been mixed (see Hussong, Ennett, Cox, & Haroon, 2017; Ning, Gondek, Patalay, & Ploubidis, 2020 for systematic reviews). One reason for mixed findings could be the effects of co-occurring externalizing problems.
-
Mar 14, 2024 | 
onlinelibrary.wiley.com | Yanan Wang |Jingjing Chen |Chen Wang |Tong Chen
• , , , et al. Evaluating the effectiveness of GTM-1, rapamycin, and carbamazepine on autophagy and Alzheimer disease . Med Sci Monit. ; : - . doi:10.12659/MSM.898679• , , , , . Resveratrol as a natural regulator of autophagy for prevention and treatment of cancer . Onco Targets Ther. ; : - . doi:10.2147/OTT.S213043• , , , , . Cellular stress responses, the Hormesis paradigm, and Vitagenes: novel targets for therapeutic intervention in neurodegenerative disorders . Antioxid Redox Signal. ; ( ): - .
-
Sep 5, 2023 | 
mdpi.com | Tong Chen |Mo Wang |Jin Su |Jianjun Li
1. IntroductionIn accordance with United Nations projections, the world’s urban populace will experience an increment of 2.5 billion by 2050 []. The burgeoning urbanization, however, imposes significant environmental, economic, and social burdens on cities [,]. These challenges range from amplified poverty, unemployment, crime rates, and political unrest to intensifying environmental concerns such as biodiversity loss, pollution, and an escalating frequency of natural disasters.
