Priit Palta

Nov 6, 2024 | nature.com | Ville Salo |Eeva Sliz |Ene Reimann |Reedik Mägi |Priit Palta |Juhani Määttä

AbstractGiven that lumbar disc herniation (LDH) is a prevalent spinal condition that causes significant individual suffering and societal costs, the genetic basis of LDH has received relatively little research. Our aim is to increase understanding of the genetic factors influencing LDH. We perform a genome-wide association analysis (GWAS) of LDH in the FinnGen project and in Estonian and UK biobanks, followed by a genome-wide meta-analysis to combine the results.