Qiao Tang

Sep 9, 2024 | pubs.rsc.org | Qiao Tang |Oxford Road |Matthew I. Gibson

Covalent recruitment of polymers and nanoparticles onto glycan-engineered cells enhances gene delivery during short exposure† Non-viral gene delivery with cationic polymers/nanoparticles relies on iterative optimization of the carrier to achieve delivery. Here we demonstrate, instead, that precision engineering of cell surfaces to covalently capture a polyplex accelerates gene delivery within just 10 min of exposure.

Jul 30, 2024 | onlinelibrary.wiley.com | Qiuling Liu |Qiao Tang |Jiayi Chen |Sufen Peng

Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202404563-sup-0001-SuppMat.docx6.5 MB Supporting Information References 1a) , , Lancet Neurol. 2023, 22, 645; b) , , , , , , , , , , , , , , , , , Nat. Nanotechnol. 2023, 18, 1230. 2a) , , , , , Nat. Rev. Neurosci. 2022, 23, 23; b) , , , , , , , , Cell 2018, 173, 153; c) , , , , , , , , , , , Nat. Commun. 2019, 10, 518. 3, , , , , , , , , , , Nat. Med.