Qihui Liu

Nov 28, 2024 | nature.com | Yuanyuan Li |Qihui Liu |Wei Zhang

AbstractConsiderable advances have been achieved in the application of nanomaterials for immunotherapies, yet the precise immune effects induced by protein corona remain elusive. Here, we explore the formation mechanism and immune regulation process of protein corona in acute myeloid leukaemia (AML) mouse models using commercialized iron oxide nanoparticles (IONPs), with different surface modifications, including an FDA-approved variant.