Qing He

Nov 8, 2024 | nature.com | Qing He |Feng Wang |Michael E. O’Donnell

Correction to: Nature Communications https://doi.org/10.1038/s41467-024-52257-x, published online 08 September 2024In the original version of the published article, the Supplementary Information was missing Supplementary Fig. 9. This has now been replaced.

Sep 8, 2024 | nature.com | Qing He |Feng Wang |Michael E. O’Donnell

AbstractIn eukaryotes, the leading strand DNA is synthesized by Polε and the lagging strand by Polδ. These replicative polymerases have higher processivity when paired with the DNA clamp PCNA. While the structure of the yeast Polε catalytic domain has been determined, how Polε interacts with PCNA is unknown in any eukaryote, human or yeast. Here we report two cryo-EM structures of human Polε–PCNA–DNA complex, one in an incoming nucleotide bound state and the other in a nucleotide exchange state.

Sep 6, 2024 | mdpi.com | Taoxu Yan |Junyao Cheng |Qing He |Yifan Wang

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Aug 21, 2024 | mdpi.com | Qing He |Sijia Lu |Jia Wang |Chang Xu

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.

May 25, 2024 | analyticalsciencejournals.onlinelibrary.wiley.com | Xin Shi |Qing He |Wei Wu Tan |Yuwen Lu

CONFLICT OF INTEREST STATEMENT The authors have declared no conflicts of interest. Supporting Information Filename Description elps7991-sup-0001-SuppMat.docx27 KB Supporting Information REFERENCES 1. The motion of rigid particles in a shear flow at low Reynolds number. J Fluid Mech. 2006; 14(2): 284–304. 2, , . Microfluidic approaches for cancer cell detection, characterization, and separation. Lab Chip. 2012; 12(10): 1753–1767. 3, , .