Qiuyun Zhang

Oct 30, 2024 | pubs.rsc.org | Xiaohua Zheng |Qiuyun Zhang |Xiaohui Wang |Jiayi Chen

Recent progress of porphyrin metal-organic frameworks for combined photodynamic therapy and hypoxia-activated chemotherapy Nanoscale metal-organic frameworks integrated with porphyrins (Por-nMOFs) have emerged as efficient nanoplatforms for photodynamic therapy (PDT), which relies on the conversion of molecular oxygen into cytotoxic singlet oxygen. However, the hypoxic microenvironment within tumors significantly limits the efficacy of PDT.