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Sep 25, 2024 | 
lexology.com | Jason N. Linder |Adam Hickey |J. Gregory Deis |Gina M. Parlovecchio |Juliet Gunev |Glen Kopp | +3 more
On September 23, 2024, Principal Deputy Assistant Attorney General Nicole M.
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Jul 3, 2024 | 
legaleraonline.com | Ravi Shah
M&A Outlook Post General Elections In IndiaWhile the new government has just come into power after an intense election campaigning, the upcoming main budget this month and measures taken by the government in the coming quarter will be crucial to set the stage for economic and M&A outlook for India. After a record high in the year 2022, M&A activity in India saw a three-year low in 2023 owing to numerous factors such as growing interest rates, global economic slowdown and geopolitical risks.
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Jun 28, 2024 | 
icma.org | Ravi Shah
Across the United States, inner-ring suburbs are struggling with visible signs of wear and tear in their once-thriving prime retail centers, mostly located at prominent intersections with high visibility. The surge in competition from revitalized metropolitan downtowns and outer-ring suburbs poses formidable challenges for these transitional communities, manifesting in the decline of property values and market share.
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Apr 11, 2024 | 
taxguru.in | Ravi Shah
On the 10th and 11th of April 2024, the All Gujarat Federation of Tax Consultants (AGFTC) and the Income Tax Bar Association (ITBA), Ahmedabad, encountered significant challenges with the GST portal’s functionality. In this letter addressed to Hon’ble Smt. Nirmala Sitharaman, the Finance Minister, they emphasize the critical nature of the issue and the impact it has on taxpayers and tax practitioners.
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Mar 28, 2024 | 
hcplive.com | Ravi Shah
Acute severe ulcerative colitis (ASUC) is managed with corticosteroids; however, approximately 30 - 40% of patients are refractory to corticosteroids and require medical or surgical rescue therapy. Corticosteroid refractoriness may be attributed to genetics as well as expression of pro-inflammatory cytokines. Downstream signaling of interleukin 2 (IL-2) prevents glucocorticoid receptor translocation, but this may be dampened by Janus kinase (JAK) inhibition. Singh et al.
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Aug 12, 2023 | 
mdpi.com | Jonathan P Tyrer |Ravi Shah |Richard Miller |Chrysothemis Paraskevopoulou
5. Numerical ResultsThis section presents and evaluates the results with some meaningful reasoning towards the models’ responses to the excavation based on the numerical findings while comparing the 2D and 3D analyses. 5.1. PLAXIS2D and RS2 AnalysisThe PLAXIS2D simulation revealed full settlement profiles (Figure 8a) for each of the constitutive models after the installation of the final lining, as well as a soil element test for calibration.
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Jun 29, 2023 | 
hcplive.com | Ravi Shah
Therapies with novel mechanisms of action are required to treat patients suffering from moderate to severe Crohn’s disease. Given that Janus kinase (JAK)-mediated activation of signal transducers and activators of transcription (STATs) in T cells contribute to the pathogenesis of Crohn’s disease, JAK inhibition is hypothesized to be a potential therapeutic target.
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Feb 2, 2023 | 
jdsupra.com | Lawrence Cunningham |Ravi Shah
Public company executives have long engaged with their shareholders, especially during proxy season, to share business strategy and address investor concerns. In recent years, public company directors have increasingly been asked to participate in the process and such engagements now may occur year-round. While there can be advantages to director-shareholder engagement, the new practice poses challenges boards should consider before proceeding.
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Feb 2, 2023 | 
pubs.rsc.org | Harsh V Thakkar |Lokesh Sharma |Ravi Shah |Rameswari Eerla
A Rapid Discriminative Hydrogen-Deuterium Exchange and LC-HRMS/MS Strategy for Primary and Higher Order Structural Mapping of Therapeutic Proteins: Filgrastim A Case Study
Harsh
Thakkar,
Rameswari
Eerla,
Lokesh
Sharma
and
Ravi P
Shah
Abstract
A vast number of therapeutic proteins, are approved and available in the market.
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Feb 1, 2023 | 
lexblog.com | Lawrence Cunningham |Ravi Shah
In recent years, public company directors have increasingly been asked to engaged with their shareholders. In this Across the Board post, Mayer Brown’s Larry Cunningham and Ravi Shah discuss issues to consider when devising a policy that balances the potential advantages and costs of director-shareholder engagement. Mayer Brown’s newest resource, Across the Board™, provides private and public companies and their boards with the latest updates, alerts, and resources in one convenient place.
