Rebeca Benavente

Oct 9, 2024 | digitalcommons.library.tmc.edu | Rebeca Benavente |J Reed |Rodrigo Morales |Mitch Lockwood

Chronic wasting disease (CWD) is a prion disease affecting cervids. CWD diagnosis is conducted through enzyme-linked immunosorbent assay (ELISA) and immunohistochemistry (IHC) in retropharyngeal lymph nodes. Unfortunately, these techniques have limited sensitivity against the biomarker (CWD-prions).

Oct 9, 2024 | digitalcommons.library.tmc.edu | Paulina Soto |Francisca Bravo-Risi |Rebeca Benavente |Stuart Siegfried Lichtenberg

AbstractChronic wasting disease (CWD) prions cause fatal neuropathies in farmed and free-ranging cervids. The deposition of prions in natural and humanmade environmental components has been implicated as a major mechanism mediating CWD spread in wild and captive populations. Prions can be deposited in the environment through excreta, tissues, and carcasses from pre-clinical and clinical animals.