Rebecca B Stowe

Oct 31, 2024 | digitalcommons.library.tmc.edu | Alison Bates |Lauryn Cook |Rebecca B Stowe |Elizabeth M Travis

Publication Date6-4-2023JournalBiochemical and Biophysical Research CommunicationsAbstractKCNQ1, the major component of the slow-delayed rectifier potassium channel, is responsible for repolarization of cardiac action potential. Mutations in this channel can lead to a variety of diseases, most notably long QT syndrome. It is currently unknown how many of these mutations change channel function and structure on a molecular level.