Articles

  • 1 month ago | sciencealert.com | Rebecca L. Dyer

    Analysis of human brain tissue revealed differences in how immune cells behave in brains with Alzheimer's disease compared to healthy brains, indicating a potential new treatment target. University of Washington-led research, published in 2023, discovered microglia in the brains of people with Alzheimer's disease were in a pre-inflammatory state more frequently, making them less likely to be protective.

  • Jan 19, 2025 | sciencealert.com | Rebecca L. Dyer

    Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for Parkinson's disease from cell-to-cell in the brain. Promisingly, an FDA-approved cancer drug that targets another protein called Lag3 – which interacts with Aplp1 – blocks the spread in mice, suggesting a potential therapy may already exist.

  • Dec 17, 2024 | sciencealert.com | Rebecca L. Dyer

    Driving an ambulance or taxi as your job may provide some protection against Alzheimer's, according to a new study that discovered these occupations have the lowest rates of death associated with the disease. Researchers analyzed US death certificates for almost 9 million people who died during 2020–2022, linking occupational data across 443 professions with Alzheimer's as a cause of death.

  • Dec 3, 2024 | sciencealert.com | Rebecca L. Dyer

    Using cannabis may cause changes in the human body's epigenome, a study of over 1,000 adults suggests. The epigenome functions like a set of switches, activating or deactivating genes to change how our bodies function. "We observed associations between cumulative marijuana use and multiple epigenetic markers across time," explained epidemiologist Lifang Hou from Northwestern University when the research was published in 2023.

  • Nov 13, 2024 | sciencealert.com | Rebecca L. Dyer

    Analysis of human brain tissue revealed differences in how immune cells behave in brains with Alzheimer's disease compared to healthy brains, indicating a potential new treatment target. University of Washington-led research, published in 2023, discovered microglia in the brains of people with Alzheimer's disease were in a pre-inflammatory state more frequently, making them less likely to be protective.

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