Reynald Evan Tugade

Nov 28, 2023 | japscjournal.com | Siaw San Hwang |Yash Sharma |Billy Joseph David |Reynald Evan Tugade

Average (ratings) Abstract Telomeres are short repetitive hexanucleotides located at the ends of eukaryotic DNA sequences. They progressively shorten with each mitotic cycle, and telomerase counteracts the process by regulating and extending the telomeres. Ageing, oxidative stress and inflammation are predisposing factors that accelerate telomere shortening, and eventually drive cells to senescence.

Nov 28, 2023 | japscjournal.com | Billy Joseph David |Reynald Evan Tugade |Ferdinand Jr Gerodias |Yash Sharma

Average (ratings) Abstract The COVID-19 pandemic is a significant worldwide health emergency. Due to the high incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, there are increasingly recognisable early and long-term outcomes of the disease. One of the uncommon complications of SARS-CoV-2 infection is multisystem inflammatory syndrome in adults (MIS-A).

Nov 28, 2023 | japscjournal.com | Leslie Bahn Kawa |Yash Sharma |Billy Joseph David |Reynald Evan Tugade

Heart failure is a leading cause of death and morbidity worldwide.1 It has a protean clinical history punctuated by recurrent hospitalisation after the initial diagnosis that is characterised by progressive deterioration in the cardiac structural and functional status of patients without interventions.2 Heart failure mortality remains high, despite the advancement in treatment modalities.3 Pharmacological treatment of heart failure has significantly reduced this burden over the past three...