Siaw San Hwang

Nov 28, 2023 | japscjournal.com | Siaw San Hwang |Yash Sharma |Billy Joseph David |Reynald Evan Tugade

Average (ratings) Abstract Telomeres are short repetitive hexanucleotides located at the ends of eukaryotic DNA sequences. They progressively shorten with each mitotic cycle, and telomerase counteracts the process by regulating and extending the telomeres. Ageing, oxidative stress and inflammation are predisposing factors that accelerate telomere shortening, and eventually drive cells to senescence.