Reza Shariatgorji

1 month ago | dx.doi.org | Reza Shariatgorji |Michael Niehues |Anna Nilsson |Tina B. Angerer

Mass spectrometry imaging (MSI) methods, namely matrix-assisted laser desorption/ionization (MALDI) and desorption electrospray ionization (DESI), are powerful label-free imaging tools capable of generating comprehensive molecular maps directly from biological tissue sections, exhibiting high sensitivity and near to cellular lateral resolution. (1) MSI has been shown to be a potentially useful technique for the spatial quantitative analysis of small molecules across tissue sections.

1 month ago | pubs.acs.org | Reza Shariatgorji |Michael Niehues |Anna Nilsson |Tina B. Angerer

Mass spectrometry imaging (MSI) methods, namely matrix-assisted laser desorption/ionization (MALDI) and desorption electrospray ionization (DESI), are powerful label-free imaging tools capable of generating comprehensive molecular maps directly from biological tissue sections, exhibiting high sensitivity and near to cellular lateral resolution. (1) MSI has been shown to be a potentially useful technique for the spatial quantitative analysis of small molecules across tissue sections.

2 months ago | pubs.acs.org | Patrik Bjärterot |Anna Nilsson |Reza Shariatgorji |Theodosia Vallianatou

Analytical ChemistryCite this: Anal. Chem. 2025, XXXX, XXXClick to copy citationCitation copied!. This publication is licensed under CC-BY 4.0 . You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters below:Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator.

2 months ago | dx.doi.org | Patrik Bjärterot |Anna Nilsson |Reza Shariatgorji |Theodosia Vallianatou

IntroductionClick to copy section linkSection link copied!Metabolomic analysis using mass spectrometry imaging (MSI), through matrix-assisted laser desorption/ionization (MALDI), has emerged as a crucial tool for studying the spatial distribution of metabolites in biological tissues, (1−3) providing insights into the metabolic heterogeneity of tissues. When applied to biological tissues, MALDI-MSI can produce hundreds or even thousands of mass-to-charge (m/z) features in a single experiment.