Richard D. Tilley

Nov 23, 2023 | pubs.rsc.org | Seyed Arman |Richard D. Tilley |John Gooding

A review of electrochemical impedance as a tool for examining cell biology and subcellular mechanisms: merits, limits, and future prospects Herein the development of cellular impedance biosensors, electrochemical impedance spectroscopy, and the general principles and terms associated with the cell-electrode interface is reviewed. This family of techniques provides quantitative and sensitive information into cell responses to stimuli in real-time with high temporal resolution.

Oct 23, 2023 | nature.com | Juanfang Ruan |Jitendra Mata |Richard D. Tilley

AbstractSoft materials in nature are formed through reversible supramolecular assembly of biological polymers into dynamic hierarchical networks. Rational design has led to self-assembling peptides with structural similarities to natural materials. However, recreating the dynamic functional properties inherent to natural systems remains challenging.

Sep 13, 2023 | biorxiv.org | Ying Yang |Yuanqing Ma |Richard D. Tilley |Katharina Gaus

AbstractStochastic optical reconstruction microscopy (STORM) allows widefield imaging with single molecule resolution through calculating the coordinates of individual fluorophores from the separation of the fluorophore emission in both time and space. Such separation is achieved by photoswitching the fluorophores between a long lived OFF state and an emissive ON state.