Richard J. Weinberg

Dec 1, 2023 | eneuro.org | Kristina D Micheva |Richard J. Weinberg |Stephen Smith |James S. Trimmer

connectivityelectron microscopynanoscaleproteomesynaptomeultrastructureSignificance StatementArray tomography (AT) is a powerful volume microscopy technique for high-dimensional analysis of complex protein populations in cells and organelles, including synapses. AT involves the use of ultrathin serial sections embedded in resin and subjected to multiple rounds of immunofluorescence antibody (Ab) labeling and imaging.