Rina Zelmann

Aug 13, 2024 | nature.com | Rina Zelmann |Peter N. Hadar |R. Mark Richardson |Ziv M. Williams |Sydney S. Cash |Corey Keller

AbstractTheta-burst stimulation (TBS), a patterned brain stimulation technique that mimics rhythmic bursts of 3–8 Hz endogenous brain rhythms, has emerged as a promising therapeutic approach for treating a wide range of brain disorders, though the neural mechanism of TBS action remains poorly understood. We investigated the neural effects of TBS using intracranial EEG (iEEG) in 10 pre-surgical epilepsy participants undergoing intracranial monitoring.

Mar 29, 2023 | nature.com | Fangyun Tian |David Zhou |Gustavo A. Balanza |Angelique C. Paulk |Rina Zelmann |Noam Peled | +5 more

AbstractKetamine produces antidepressant effects in patients with treatment-resistant depression, but its usefulness is limited by its psychotropic side effects. Ketamine is thought to act via NMDA receptors and HCN1 channels to produce brain oscillations that are related to these effects.