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Nov 25, 2024 | 
ravallirepublic.com | Rocky Mountain Laboratories
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May 21, 2024 | 
journals.plos.org | David Bland |Rocky Mountain Laboratories |Dan Long
Loading metrics Open Access Peer-reviewed Short Reports Short Reports offer exciting novel biological findings that may trigger new research directions. See Journal Information» Citation: Bland DM, Long D, Rosenke R, Hinnebusch BJ (2024) Yersinia pestis can infect the Pawlowsky glands of human body lice and be transmitted by louse bite. PLoS Biol 22(5): e3002625.
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May 1, 2024 | 
retrovirology.biomedcentral.com | Rocky Mountain Laboratories
Human immune system mice were generated by engraftment of cord blood-derived stem cells into immune deficient and irradiated mice. NOD.Cg-PrkdcSCIDIl2rgtm1Wjl/SzJ (or NSG) mice (Jackson Laboratory) at 3–4 weeks of age received a sublethal radiation dose of 125 cGY exposure in a RS 2000 small animal irradiator.
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May 1, 2024 | 
link.springer.com | Rocky Mountain Laboratories
AbstractThe study of HIV infection and pathogenicity in physical reservoirs requires a biologically relevant model. The human immune system (HIS) mouse is an established model of HIV infection, but defects in immune tissue reconstitution remain a challenge for examining pathology in tissues.
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Mar 20, 2024 | 
helenair.com | Rocky Mountain Laboratories
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Jul 21, 2023 | 
academic.oup.com | Rocky Mountain Laboratories
Ebola virus (EBOV), strain Makona, infected more than 30,000 people from 2013-2016 in West Africa, among them many health care workers including foreign nationals. Most of the infected foreign nationals were evacuated and treated in their respective home countries resulting in detailed reports of the acute disease following EBOV infection as well as descriptions of symptoms now known as “Post-Ebola Syndrome” which occurred months after the infection.
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Jun 22, 2023 | 
academic.oup.com | Rocky Mountain Laboratories
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Jun 8, 2023 | 
academic.oup.com | Rocky Mountain Laboratories
When you visit web sites, they may store or retrieve data in your web browser. This storage is often necessary for basic functionality of the web site or the storage may be used for the purposes of marketing, analytics, and personalization of the web site such as storing your preferences.
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Apr 19, 2023 | 
journals.plos.org | Megan O’Connor |David W Hawman |Rocky Mountain Laboratories |PLOS Pathogens
The repRNA-CoV2S vaccine affords durable protection from SARS-CoV-2 induced clinical disease and pathologyWe next evaluated the ability of the vaccine to protect from clinical disease and lung pathology. Animals were comprehensively evaluated by trained research staff for evidence of disease including reduced appetite, lethargy, respiratory distress, and general appearance. The most common clinical observations among unvaccinated animals were lethargy, abnormal respiration, and nasal discharge.
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Feb 14, 2023 | 
actaneurocomms.biomedcentral.com | Rocky Mountain Laboratories
Human cerebral organoids offer a powerful model of brain tissue in a dish that can be used to investigate neurodegenerative disorders. Our previous work showed that cerebral organoids could be infected with sCJD prions derived from human brain tissue. However, as organoids represent, but are not actual brain tissue, it was imperative to determine if the prions propagated within them were the original subtype or adaptations.
