
Ronan Chaligné
Articles
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2 weeks ago |
nature.com | Xueqian Zhuang |Alexander Ferrena |David Humphreys |Melissa Blum |Yingqian A Zhan |Yang Zhao | +10 more
Correction to: Nature https://doi.org/10.1038/s41586-024-08285-0 Published online 4 December 2024In the version of the article initially published, the “Transferrin” inset image in Fig. 5b was missing and has now been included in the HTML and PDF versions of the article. About this articleZhuang, X., Wang, Q., Joost, S. et al. Publisher Correction: Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis. Nature (2025).
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Jan 8, 2025 |
nature.com | Robert R. Stickels |Zaki Abou-Mrad |Viviane Tabar |Brooke E. Howitt |Leif S. Ludwig |Ronan Chaligné | +1 more
AbstractSingle-cell genomics technologies have accelerated our understanding of cell-state heterogeneity in diverse contexts. Although single-cell RNA sequencing identifies rare populations that express specific marker transcript combinations, traditional flow sorting requires cell surface markers with high-fidelity antibodies, limiting our ability to interrogate these populations.
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May 8, 2024 |
nature.com | Franco Izzo |Robert Myers |Levan Mekerishvili |Elliot Eton |Eleni P. Mimitou |Daniel Choi | +6 more
AbstractIn somatic tissue differentiation, chromatin accessibility changes govern priming and precursor commitment towards cellular fates1,2,3. Therefore, somatic mutations are likely to alter chromatin accessibility patterns, as they disrupt differentiation topologies leading to abnormal clonal outgrowth. However, defining the impact of somatic mutations on the epigenome in human samples is challenging due to admixed mutated and wild-type cells.
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