Rong-Hui Xia

Aug 4, 2023 | frontiersin.org | Takumi Kumai |Rong-Hui Xia |Michihisa Kono

1 IntroductionIn 2010, Skalova et al. reported a histological type of salivary gland carcinoma that resembled the secretory carcinoma (SC) of the mammary gland, known as mammary analog secretory carcinoma (MASC) (1). Recently, MASC was established as a new histologic type in the World Health Organization Classification of Head and Neck Tumors (4th edition) as SC (2). SCs are low-grade salivary gland tumors that grow relatively slowly (1, 3, 4); however, there is currently no effective drug therapy.