Rowan Howell

Apr 12, 2023 | science.org | Yu Jiang |Rowan Howell |Yuwei Song |Yingpu Yu

DISCUSSIONHere, we report a cell culture–based method to study HBV, which has several unique advantages compared to other commonly used approaches. One of the main advantages is the near absence of HBV DNA and HBsAg signal from input material.

Apr 12, 2023 | science.org | Yu Jiang |Rowan Howell |Yuwei Song |Li Tang

AbstractThe extreme environments of the Tibetan Plateau offer considerable challenges to human survival, demanding novel adaptations. While the role of biological and agricultural adaptations in enabling early human colonization of the plateau has been widely discussed, the contribution of pastoralism is less well understood, especially the dairy pastoralism that has historically been central to Tibetan diets.

Apr 12, 2023 | science.org | Yu Jiang |Rowan Howell |Yuwei Song |Yi Zhou

Functional adhesion and detachment for skin flap survivalTo verify the potential of the reversible bioadhesive, we established a mouse model of random skin flap transplantation, an important method for severe wound repair (71). Tissue adhesive may be a promising application to shorten the operation time and rapidly recover blood perfusion. Four pieces of film adhesive were placed on the edges of the flap for stable fixation to substitute for traditional suturing (Fig. 5A).

Apr 12, 2023 | science.org | Yu Jiang |Rowan Howell |Yuwei Song |Zhuang Zhang

AbstractSoft structures and actuation allow robots, conventionally consisting of rigid components, to perform more compliant, adaptive interactions similar to living creatures. Although numerous functions of these types of actuators have been demonstrated in the literature, their hyperelastic designs generally suffer from limited workspaces and load-carrying capabilities primarily due to their structural stretchability factor.

Apr 12, 2023 | science.org | Yu Jiang |Rowan Howell |Yuwei Song |Junyao Yang

AbstractCD34+ cells improve the perfusion and function of ischemic limbs in humans and mice. However, there is no direct evidence of the differentiation potential and functional role of these cells in the ischemic muscle microenvironment.