Rubèn Gonzàlez-Colom

Aug 20, 2024 | nature.com | András Gézsi |Rubèn Gonzàlez-Colom |Xenia Gonda |Linda Garvert |Zsofia Gal |Carsten Schmidt | +4 more

AbstractThe heterogeneity and complexity of symptom presentation, comorbidities and genetic factors pose challenges to the identification of biological mechanisms underlying complex diseases. Current approaches used to identify biological subtypes of major depressive disorder (MDD) mainly focus on clinical characteristics that cannot be linked to specific biological models. Here, we examined multimorbidities to identify MDD subtypes with distinct genetic and non-genetic factors.

Jun 28, 2024 | ijic.org | Carmen Herranz |Alba Gómez |Carme Hernandez |Rubèn Gonzàlez-Colom

IntroductionComplex chronic patients, as defined in [], frequently face unplanned hospitalizations, either due to episodes of exacerbation, or during periods associated with increased vulnerability, like the transition from hospital to the community after hospital discharge []. It is widely accepted that unplanned hospital admissions generate significant dysfunctions, and a high financial burden, on healthcare systems worldwide [].