Xenia Gonda

Aug 20, 2024 | nature.com | András Gézsi |Rubèn Gonzàlez-Colom |Xenia Gonda |Linda Garvert |Zsofia Gal |Carsten Schmidt | +4 more

AbstractThe heterogeneity and complexity of symptom presentation, comorbidities and genetic factors pose challenges to the identification of biological mechanisms underlying complex diseases. Current approaches used to identify biological subtypes of major depressive disorder (MDD) mainly focus on clinical characteristics that cannot be linked to specific biological models. Here, we examined multimorbidities to identify MDD subtypes with distinct genetic and non-genetic factors.

May 2, 2023 | frontiersin.org | Xenia Gonda

Suicide is a growing public health problem (1, 2). It can be seen in a wide range of people, from mentally healthy individuals who react to challenging living conditions to patients with severe mental disorders (3–5). Suicide has complex biological, social, and psychological risk factors and a multidimensional clinical presentation (6, 7). Recent studies have revealed the complexity underlying the neurobiological mechanisms of suicide (8–12).