Ruth Baker

May 21, 2024 | biorxiv.org | Isaac B Breinyn |Ruth Baker |Daniel Cohen

AbstractEpithelial migration is implicit in processes ranging from gastrula development to the healing of skin, and involves the coordinated motion, force production, and resulting energy expenditure of thousands of constitutive cells. However, the spatiotemporal patterning and regulation of energy expenditure during epithelial migration remains poorly understood. Here, we propose a continuum mechanics framework and use it to explore how energy expenditure regulates epithelial migration.