Ryan Cook

Dec 19, 2023 | biorxiv.org | Ryan Cook |Andrea Telatin |George Bouras |Antonio Pedro Camargo

AbstractThe majority of bacteriophage diversity remains uncharacterised, and new intriguing mechanisms of their biology are being continually described. Members of some phage lineages, such as the Crassvirales, repurpose stop codons to encode an amino acid by using alternate genetic codes. Here, we investigated the prevalence of stop codon reassignment in phage genomes and subsequent impacts on functional annotation.