Ryan D. Heselpoth

Sep 25, 2023 | mdpi.com | Ryan D. Heselpoth |Frederick P. Schwarz |Daniel Nelson |J. Todd Hoopes

1. IntroductionThe increasing global threat of bacterial resistance to traditional antibiotics highlights the need for alternative antimicrobials [1,2,3,4]. One potential antimicrobial strategy involves the use of bacteriophage (or phage)-encoded endolysins [5,6]. These enzymes are primarily peptidoglycan (i.e., cell wall) hydrolases that cleave critical covalent bonds in the cell wall of phage-infected bacteria.

Aug 1, 2023 | biorxiv.org | James Hoopes |Ryan D. Heselpoth |Daniel Nelson |Frederick P. Schwarz

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