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3 weeks ago | 
cshl.edu | Samuel Diamond
You are not the same person you were a decade ago. Most of your body’s cells are replaced every seven to 10 years. Nevertheless, you retain the genes and memories that help make you, you. Science still doesn’t fully understand how the aging process works. But we’re getting closer, and the answers may hold the key to finally conquering diseases and disorders that humans have been struggling with for centuries.
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1 month ago | 
phys.org | Samuel Diamond |Sadie Harley |Robert Egan
Numbers have a funny way about them. Young math students are taught various strategies to make problem-solving easier. Comparing fractions? Find a common denominator or convert to decimals. The strategies get more complex when doing the kind of math used to describe the activities of DNA, RNA, or protein sequences.
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1 month ago | 
cshl.edu | Samuel Diamond
The Takeaway CSHL Associate Professors Justin Kinney and David McCandlish have developed a unified theory for mathematical parameters known as gauge freedoms. Their new formulas will allow scientists to interpret research results much faster and with greater confidence. The development could prove fundamental for future efforts in agriculture, drug discovery, and beyond.
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1 month ago | 
cshl.edu | Samuel Diamond
When there’s this much courage and innovation in one space, you can almost feel it in the air. It’s an understanding, a sense that everyone here shares the same mission: to improve people’s lives and help make the world a better place. Imagine the possibilities. On November 19, Cold Spring Harbor Laboratory (CSHL) will host its 20th annual Double Helix Medals dinner at the American Museum of Natural History.
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2 months ago | 
cshl.edu | Samuel Diamond
Cold Spring Harbor Laboratory (CSHL) Professor John Moses has been named a Fellow of the Learned Society of Wales. He is one of 56 leaders and experts elected to this prestigious role from academia, health services, and the public sphere. At CSHL, Moses uses a revolutionary process called click chemistry to identify and test potential new treatments for cancers, infections, and neurological conditions.
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2 months ago | 
cshl.edu | Samuel Diamond
The Takeaway CSHL Professor David Tuveson and Research Investigator Claudia Tonelli have found a way to “intercept” pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to prevent pancreatic cancer from forming in the first place.
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2 months ago | 
cshl.edu | Samuel Diamond
As the world’s population ages, neurodegenerative conditions like Alzheimer’s disease are becoming more and more common. Alzheimer’s is the leading cause of dementia. And though research into these conditions has yielded many fascinating results, few have translated to clinical applications. Today, we have a better idea of what Alzheimer’s does to the brain. However, we’re still a long way from figuring out how to cure the disease or prevent it from taking hold in the first place.
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Mar 11, 2025 | 
cshl.edu | Samuel Diamond
For science to positively impact the world, it must be shared. It must be circulated among scientists and communicated with the public. Over the past decade, the free online platforms bioRxiv and medRxiv, developed at Cold Spring Harbor Laboratory (CSHL), have revolutionized how biomedical research is shared around the world. Accelerating their success now becomes the mission of openRxiv, a newly launched, community-oriented, independent nonprofit. bioRxiv was founded in 2013, and medRxiv in 2019.
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Feb 14, 2025 | 
cshl.edu | Samuel Diamond
The Takeaway In a new study, Cold Spring Harbor Laboratory Professor Hiro Furukawa and postdoc Hyunook Kang prove the existence of a mysterious brain receptor known as GluN1-2B-2D. They also show several ways the drug ketamine can interact with GluN1-2B-2D. Their research may lead to safer treatments for depression, anxiety, and other mental health conditions.
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Jan 27, 2025 | 
cshl.edu | Samuel Diamond
Cold Spring Harbor Laboratory Associate Professor Tobias Janowitz has been elected to the American Society for Clinical Investigation (ASCI). Janowitz is recognized for his outstanding scholarly research, which approaches cancer from a whole-body perspective. He has led clinical trials and published authoritative studies on cancer cachexia, a debilitating condition that affects patients in the late stages of the disease. “I am pleased to become a member of the ASCI,” says Janowitz.
