Cold Spring Harbor Laboratory

Established in 1890, Cold Spring Harbor Laboratory has played a pivotal role in advancing modern biomedical research and education, focusing on areas such as cancer, neuroscience, plant biology, and quantitative biology. The private, non-profit institution boasts eight Nobel Prize laureates among its staff of 1,000, which includes 600 scientists, students, and technicians. Each year, the Meetings & Courses Program attracts over 12,000 scientists from across the globe to its campuses located in Long Island and Suzhou, China. Additionally, the Laboratory's educational initiatives encompass an academic publishing division, a graduate school, and various programs designed for middle and high school students, as well as undergraduates and educators.

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In nature’s math, freedoms are fundamental

1 week ago | cshl.edu | Samuel Diamond

The Takeaway CSHL Associate Professors Justin Kinney and David McCandlish have developed a unified theory for mathematical parameters known as gauge freedoms. Their new formulas will allow scientists to interpret research results much faster and with greater confidence. The development could prove fundamental for future efforts in agriculture, drug discovery, and beyond.
CSHL to honor Chris Evert, Martina Navratilova & Bob Langer

3 weeks ago | cshl.edu | Samuel Diamond

When there’s this much courage and innovation in one space, you can almost feel it in the air. It’s an understanding, a sense that everyone here shares the same mission: to improve people’s lives and help make the world a better place. Imagine the possibilities. On November 19, Cold Spring Harbor Laboratory (CSHL) will host its 20th annual Double Helix Medals dinner at the American Museum of Natural History.
Moses elected Fellow of Learned Society of Wales

1 month ago | cshl.edu | Samuel Diamond

Cold Spring Harbor Laboratory (CSHL) Professor John Moses has been named a Fellow of the Learned Society of Wales. He is one of 56 leaders and experts elected to this prestigious role from academia, health services, and the public sphere. At CSHL, Moses uses a revolutionary process called click chemistry to identify and test potential new treatments for cancers, infections, and neurological conditions.
In pancreatic cancer, a race against time

2 months ago | cshl.edu | Samuel Diamond

The Takeaway CSHL Professor David Tuveson and Research Investigator Claudia Tonelli have found a way to “intercept” pancreatic cancer. By inhibiting the cancer gene FGFR2, they were able to slow tumor formation. By targeting the FGFR2 and EGFR proteins, they were able to prevent pancreatic cancer from forming in the first place. Your browser does not support the audio element.
Lucas Cheadle awarded $750K MIND Prize

2 months ago | cshl.edu | Samuel Diamond

As the world’s population ages, neurodegenerative conditions like Alzheimer’s disease are becoming more and more common. Alzheimer’s is the leading cause of dementia. And though research into these conditions has yielded many fascinating results, few have translated to clinical applications. Today, we have a better idea of what Alzheimer’s does to the brain. However, we’re still a long way from figuring out how to cure the disease or prevent it from taking hold in the first place.
The natural evolution of bioRxiv and medRxiv

2 months ago | cshl.edu | Samuel Diamond

For science to positively impact the world, it must be shared. It must be circulated among scientists and communicated with the public. Over the past decade, the free online platforms bioRxiv and medRxiv, developed at Cold Spring Harbor Laboratory (CSHL), have revolutionized how biomedical research is shared around the world. Accelerating their success now becomes the mission of openRxiv, a newly launched, community-oriented, independent nonprofit. bioRxiv was founded in 2013, and medRxiv in 2019.
Ketamine: From club drug to antidepressant?

Feb 14, 2025 | cshl.edu | Samuel Diamond

The Takeaway In a new study, Cold Spring Harbor Laboratory Professor Hiro Furukawa and postdoc Hyunook Kang prove the existence of a mysterious brain receptor known as GluN1-2B-2D. They also show several ways the drug ketamine can interact with GluN1-2B-2D. Their research may lead to safer treatments for depression, anxiety, and other mental health conditions.
Janowitz elected to ASCI

Jan 27, 2025 | cshl.edu | Samuel Diamond

Cold Spring Harbor Laboratory Associate Professor Tobias Janowitz has been elected to the American Society for Clinical Investigation (ASCI). Janowitz is recognized for his outstanding scholarly research, which approaches cancer from a whole-body perspective. He has led clinical trials and published authoritative studies on cancer cachexia, a debilitating condition that affects patients in the late stages of the disease. “I am pleased to become a member of the ASCI,” says Janowitz.
A speckle of hope for cancer patients

Jan 2, 2025 | cshl.edu | Luis Sandoval

The Takeaway New Cold Spring Harbor Laboratory Assistant Professor Katherine Alexander has identified two patterns of nuclear speckles in the most common form of kidney cancer. Her research at the University of Pennsylvania suggests speckle patterns may correlate with patient outcomes. The finding offers a new starting point in the search for personalized kidney cancer treatments.
Where are they now?

Dec 9, 2024 | cshl.edu | Margaret Osborne

Research is itself an educational activity. With the laws of science and nature for teachers, researchers conduct experiments to learn how life and the world work. Cold Spring Harbor Laboratory (CSHL) is world-renowned for breakthrough bioscience research. What many outside the scientific community might not realize is that the Laboratory was founded as an educational institute. That was all the way back in 1890.