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Sep 26, 2024 | 
nature.com | Sandeep Das |Alexandra C Finney |Sumit Anand |Alia Ghrayeb |Kelley G. Núñez |Fabio Arias | +23 more
AbstractThe incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.
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Sep 26, 2024 | nature.com | Sandeep Das |Alexandra C Finney |Sumit Anand |Alia Ghrayeb |Kelley G. Núñez |Fabio Arias | +23 more
AbstractThe incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.
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Apr 17, 2024 | 
economictimes.indiatimes.com | Sandeep Das
Risk in simple terms can be defined as that which cannot be foreseen. We live in a dynamic world where global uncertainties become an intrinsic part of the investing life cycle. We have to be on a constant watch for global factors (financial and non-financial) that could have near to long-term implications on our investments.
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Mar 20, 2024 | 
economictimes.indiatimes.com | Sandeep Das
The fate of the physical retail store has been up for discussion over the past few years. During with people confined to their houses, e-commerce went through the roof. As people stepped out of the pandemic a couple of years ago, the store did make a stunning comeback. But the question remained: Was it a ‘revenge consumption’ story or was it more fundamental? The return of the retail store There is no doubt that a physical store is the centre
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Mar 3, 2024 | 
sandeepdas9179.medium.com | Sandeep Das
In December 2023, after close to four years of Covid driven obstacles, I visited Delhi (my birthplace) with my family. We were there for three weeks, and honestly did not recognise a lot of the Delhi we knew and grew up in. The pace of change has been too fast to comprehend. During those three weeks, we got a taste of the app-driven life of urban India. I am sure that apps have had their impact on rural life and livelihoods, but it needs to be experienced to be validated.
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Jan 23, 2024 | 
economictimes.indiatimes.com | Sandeep Das
The year 2023 was considered largely a good one. It was the year when the Covid-19 pandemic was finally declared over, officially. Most retail and consumer sectors, despite some headwinds, had a good year. Now let’s weigh what 2024 has in store for retail and consumer-centric companies. Demand likely to remain steady but strained The big question on everyone’s mind is how the rural consumer is going to shape demand in 2024. Most commentaries by
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Dec 22, 2023 | 
forbesindia.com | Sandeep Das
As we come to the end of 2023, it is interesting to look back on the year gone by and the prevalent mood at the end of 2022. 2023 was the first year where COVID-19 concerns had largely receded from our daily lives, and a consumption boom, in line with the roaring 20s, was expected. Did that pan out as expected? In this article, we look at the major incidents of 2023 and what might 2024 be the harbinger of.
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Nov 20, 2023 | 
newsdirectory3.com | Sandeep Das
Indian Fans: Emotional vs ProfessionalIt seems that the clash of cultures between India and Australia has spilled over into the world of cricket, with Indian fans expressing their disappointment and frustration towards Australian cricketer Mitchell Marsh. The emotional backlash from Indian fans has raised questions about the impact of over-emotionalism on the performance of the Indian cricket team in ICC tournaments.
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Oct 20, 2023 | 
forbesindia.com | Sandeep Das
If you are looking to have a romantic relationship and are struggling with online dating apps and wooing people in real life, there’s another option: a customised AI partner. This scenario is not from the 2013 romantic sci-fi movie, 'Her', featuring Joaquin Phoenix and his AI companion, played by Scarlett Johansson, but a reality in the lives of tens of millions of people.
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Sep 30, 2023 | 
theweek.in | K. Thomas |Sandeep Das
Who doesn’t like a good story? At the movies, the story, and plot line, is the essential driver that helps us gravitate towards selecting one film over the other. The same for web series and paperbacks, and possibly, every other mode of entertainment. But have you ever wondered, every human being probably needs a story to stand apart from the crowd?
