Sumit Anand

Sep 26, 2024 | nature.com | Sandeep Das |Alexandra C Finney |Sumit Anand |Alia Ghrayeb |Kelley G. Núñez |Fabio Arias | +23 more

AbstractThe incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.

Sep 26, 2024 | nature.com | Sandeep Das |Alexandra C Finney |Sumit Anand |Alia Ghrayeb |Kelley G. Núñez |Fabio Arias | +23 more

AbstractThe incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produced from glyoxylate by hepatic lactate dehydrogenase (LDHA). The liver-specific alanine-glyoxylate aminotransferase (AGXT) detoxifies glyoxylate, preventing oxalate accumulation.

May 7, 2023 | shashank-bhardwaj.medium.com | Sumit Anand

Are you tired of hearing people brag about their six-figure earnings from freelancing or influencing on social media? Don't fall for it!It's like the old Hindi proverb, " Door ka dhol suhwana lagta hain." People only show you the happy highlights of their lives, not the struggles and hard work behind the scenes. Running your own business can be a wonderful experience, but don't quit your job before considering the reasons why:i) Are you underpaid?