Sandra K. Althouse

Jun 6, 2024 | jamanetwork.com | Victoria Sanchez |Paul Dinh |Patrick Monahan |Sandra K. Althouse

Key PointsQuestion  What factors are associated with (1) the progression of cisplatin-related hearing loss (CRHL) in survivors of adult-onset cancer and (2) performance on the Words-in-Noise test (WIN)? Findings  In this cohort study of 100 cancer survivors, poorer WIN performance was significantly associated with hypercholesterolemia, lower education, and CRHL severity; CRHL progression was significantly associated with hypercholesterolemia and age.

May 21, 2024 | acsjournals.onlinelibrary.wiley.com | Noah Richardson |Fadi Taza |Rafat Abonour |Sandra K. Althouse

INTRODUCTION Primary extragonadal germ cell tumors comprise only 5% of germ cell tumors and arise most commonly in the mediastinum in adults.1 Primary mediastinal nonseminomatous germ cell tumors (PMNSGCTs), although similar in histology and cytogenetics to testicular germ cell tumors, have less response to cisplatin-based chemotherapy and are classified as poor-risk disease regardless of other factors, such as the size of the tumor, amplitude of serum tumor markers (STMs), and other factors...