Sang-Jin Lee

May 1, 2024 | journals.plos.org | Ana I. Gonçalves |Márcia T. Rodrigues |Sang-Jin Lee |Anthony Atala

Loading metrics Errors were made during the preparation of Fig 2 which resulted in the erroneous duplication of the following panels: hAFSC 14 days EGF (incorrect panel) and hAFSC 14 days TGF-β (correct panel) hAFSC 21 days medium B (incorrect panel) and hAFSC 21 days TGF-β (correct panel) hASC 21 days TGF-β (correct panel) and hASC 28 days medium A (incorrect panel) With this correction, the authors provide a corrected version of Fig 2 as well as the original underlying representative images...

Mar 13, 2024 | nature.com | Sang-Jin Lee

AbstractProtein arginine methyltransferases (PRMTs) modulate diverse cellular processes, including stress responses. The present study explored the role of Prmt7 in protecting against menopause-associated cardiomyopathy. Mice with cardiac-specific Prmt7 ablation (cKO) exhibited sex-specific cardiomyopathy. Male cKO mice exhibited impaired cardiac function, myocardial hypertrophy, and interstitial fibrosis associated with increased oxidative stress.