Sangbhin Lee

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Liver-innervating vagal sensory neurons play an indispensable role in the development of hepatic steatosis and anxiety-like behavior in mice fed a high-fat diet.

Dec 2, 2024 | biorxiv.org | Jiyeon Hwang |Junichi Okada |li Liu |Sangbhin Lee

AbstractThe visceral organ-brain axis, mediated by vagal sensory neurons, is essential for maintaining various physiological functions. Here, we investigate the impact of liver-projecting vagal sensory neurons on energy balance, hepatic steatosis, and anxiety-like behavior in mice under obesogenic conditions.

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