Sarah B Doernberg

2 months ago | onlinelibrary.wiley.com | Sarah B Doernberg |Emily Heil |Health-Outcomes Research |Suiyini Fiawoo

Abbreviations BSI Bloodstream infection CRE Carbapenem-resistant Enterobacterales ESBL Extended-spectrum beta-lactamase GN Gram negative IQR Interquartile range SOT Solid-organ transplant 1 Introduction Gram-negative bloodstream infection (GN-BSI) occurs commonly in solid-organ transplant (SOT) patients, particularly in the first year after transplant, and carries significant morbidity and mortality [1-5].

Feb 12, 2024 | ascpt.onlinelibrary.wiley.com | Sarah B Doernberg |Travis Zack |Atul J. Butte |Anu Patel

WHAT IS THE CURRENT KNOWLEDGE ON THE TOPIC? Electronic health records (EHRs) are a valuable source of real-world data that can be utilized for analysis of drug-related adverse events (AEs) not otherwise reliable from clinical trials or pharmacovigilance efforts. Machine learning is a prediction tool that can aid clinical decision making. WHAT QUESTION DID THIS STUDY ADDRESS?